Non-invasive prenatal testing as a valuable source of population specific allelic frequencies - dataset

Budiš, Jaroslav; Gazdarica, Juraj; Radvánszky, Ján; Haršanyová, Mária; Gazdaricová, Iveta; Striešková, Lucia; Frno, Richard; Ďuriš, František; Minárik, Gabriel; Sekelská, Martina; Nagy, Balint; Szemes, Tomáš

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dc.contributor.author	Budiš, Jaroslav
dc.contributor.author	Gazdarica, Juraj
dc.contributor.author	Radvánszky, Ján
dc.contributor.author	Haršanyová, Mária
dc.contributor.author	Gazdaricová, Iveta
dc.contributor.author	Striešková, Lucia
dc.contributor.author	Frno, Richard
dc.contributor.author	Ďuriš, František
dc.contributor.author	Minárik, Gabriel
dc.contributor.author	Sekelská, Martina
dc.contributor.author	Nagy, Balint
dc.contributor.author	Szemes, Tomáš
dc.date.accessioned	2021-07-20T12:08:57Z
dc.date.available	2021-07-20T12:08:57Z
dc.date.issued	2021
dc.identifier.uri	https://dspace.uniba.sk/xmlui/handle/123456789/27
dc.description	Sequenced reads from 1501 individuals (low coverage ~0.2x) to estimate common genomic variation in Slovak population. SNP, insertion and deletion variants are available in form of VCF file. To open the file use i.e. IGV (Integrative Genomics Viewer).	en_US
dc.description.abstract	Low coverage massively parallel genome sequencing for non-invasive prenatal testing (NIPT) of common aneuploidies is one of the most rapidly adopted relatively low-cost DNA tests. Since aggregation of reads from a large amount of samples allows to overcome problems of extremely low coverage of individual samples, the possible reuse of the data generated during NIPT testing for genome scale population specific frequency determination of single nucleotide variants is described.	en_US
dc.description.sponsorship	This work was supported by the project titled “REVOGENE – Research Centre for Molecular Genetics” (ITMS 26240220067) supported by the Operational Program Research and Development funded by the European Regional Development Fund.
dc.subject	genome sequencing	en_US
dc.subject	DNA tests	en_US
dc.subject	NIPT testing	en_US
dc.subject	population specific allelic frequencies
dc.title	Non-invasive prenatal testing as a valuable source of population specific allelic frequencies - dataset	en_US
dc.type	Dataset	en_US